The exhaustive investigation of the fire and extensive reworking of the CMs postponed any manned launch until NASA officials cleared the CM for manned flight. Saturn 1B schedules were suspended for nearly a year, and the launch vehicle that finally bore the designation AS-204 carried a Lunar Module (LM) as the payload, not the Apollo CM. The missions of AS-201 and AS-202 with Apollo spacecraft aboard had been unofficially known as Apollo 1 and Apollo 2 missions (AS-203 carried only the aerodynamic nose cone). In the spring of 1967, NASA's Associate Administrator for Manned Space Flight, Dr. George E. Mueller, announced that the mission originally scheduled for Grissom, White and Chaffee would be known as Apollo 1, and said that the first Saturn V launch, scheduled for November 1967, would be known as Apollo 4. The eventual launch of AS-204 became known as the Apollo 5 mission (no missions or flights were ever designated Apollo 2 and 3).

The second launch of a Saturn V took place on schedule in the early morning of April 4, 1968. Known as AS-502, or Apollo 6, the flight was a success, though two first stage engines shut down prematurely, and the third stage engine failed to re-ignite after reaching orbit.